Scientific-Technological Objectives of the Network

GENERAL PURPOSE

The general objective of the V-Heart network is the development of a multi-scale computational model of the heart that allows progress in the study of the mechanisms that generate and maintain cardiac arrhythmias, and the study of the effects of different therapies (such as for example: pharmacological, ablation, resynchronization, etc.) in the context of personalized medicine, and contribute to the use of computational modeling in daily clinical practice by developing tools adapted to the final user, the medical professional.

SPECIFIC OBJECTIVES

• Put in common and integrate the different numerical methods and models for the development of a cardiac computational model that considers the specificity of the different types of patients.
• Help in the advancement of knowledge of the mechanisms associated with different cardiac pathologies.
• Investigate and develop applications adapted to the patient to give support in:
  – The planning of surgical interventions.
  – The optimization of the application of electrical therapies (resynchronization, defibrillation, pacemaker, etc.).
  – Predicting the efficiency of drugs and their cardiotoxicity (of interest to the pharmaceutical industry).
• Offer computational solutions to the challenges of clinical and translational research in the cardiovascular area.
• Contribute to a greater use of cardiac models in a clinical environment.
• To place the V-Heart network as a national and international point of reference in the computational modeling of the heart, strengthening the position of Spanish science.